Primary Central Nervous System Lymphoma Diagnosed by Biopsy of Skin and Sural Nerve

J Korean Neurol Assoc > Volume 27(3); 2009 > Article

Journal of the Korean Neurological Association 2009;27(3): 286-290.

피부와 장딴지신경조직검사로 확진한 원발중추신경계림프종

노상미, 김광기 최종순a

동국대학교 일산병원 신경과, 병리과a

Primary Central Nervous System Lymphoma Diagnosed by Biopsy of Skin and Sural Nerve

Sang Mi Noh

Departments of Neurology and Pathologya, Dongguk University International Hospital, Goyang, Korea

Abstract

Primary central nervous system lymphoma (PCNSL) is a rare tumor that accounts for less than 2% of all cerebral neoplasms. A 72-year-old man had been suffering from recurrent cranial nerve palsies for several years. His condition improved with steroid treatment, but then eventually worsened; he developed encephalopathic symptoms, quadriparesis, axonal neuropathy, and skin lesions. He was eventually diagnosed with PCNSL following an examination of skin and sural nerve biopsy samples. Biopsy of skin lesions or nerves should be considered for the accurate and early diagnosis of PCNSL. Key Words: Lymphoma, Peripheral nervous system, Skin