J Korean Neurol Assoc > Volume 21(2); 2003 > Article

Journal of the Korean Neurological Association 2003;21(2): 199-203.

백질 뇌증의 형태를 갖는 원발성 중추 신경계 임파종

이서영 , 홍윤호 권선주 박경석 김만호

서울대학교 의과대학 신경과학교실,인제대학교 서울백병원

"Primary Central Nervous System Lymphoma: A Notable Differential Diagnosis of Leukoencephalopathy"

Seo-Young Lee

"Department of Neurology and Clinical Research Institute, Seoul National University Hospital Department of Neurology, lnje University Seoul Paik Hospital"

Abstract

"We report a 61-year-old man presented with hyperventilation in the absence of alteration of consciousness. Brain MRI showed diffuse T2-high signal intensities in the white matter of the bilateral hemispheres and brainstem with some focal enhancements without mass effect or edema. Methionine PET demonstrated hypermetabolism in the right thala-mus and cerebellum. Primary central nervous system lymphoma (PCNSL) was confirmed pathologically by stereotaxic biopsy. PCNSL can take the form of leukoencephalopathy in MRI, and methionine PET would be helpful for the differ-entiation of PCNSL from non-tumorous conditions.Key Words : PCNSL, Leukoencephalopathy, PET"