A Case of Thrombotic Thrombocytopenic Purpura Associated with ?Large Intracerebral Hemorrhage and Peri-pheral Neuropathy

J Korean Neurol Assoc > Volume 13(2); 1995 > Article

Journal of the Korean Neurological Association 1995;13(2): 386-390.

큰 뇌출혈과 말추신경병증을 동반한 혈전성 혈소판감소성 자반증 1례

유봉구, 김광수, 유경무

고신대학교 신경과

A Case of Thrombotic Thrombocytopenic Purpura Associated with ?Large Intracerebral Hemorrhage and Peri-pheral Neuropathy

Bong Goo Yoo, M.D., Kwang Soo Kim, M.D., Kyung Mu Yoo, M.D.

Department of Neurology, Kosin Medical College

Abstract

Thrombotic thrombocytopenic purpura(TTP) is characterized by fluctuating neurologic signs, microangiopathic hemolytic anemia, thrombocytopenia, fever and renal abnormalities. Neurologic involvement occurs in over 90% of patients with TTP. TTP is rarely associated with large intracerebral hemorrhage and peripheral neuropadiy. The authors report a case of TTP associated with large intracerebral hemorrhage confirmed by brain MRI and peripheral neuropathy diagnosed electrophysiologic fin-dings and sural nerve biopsy.