A Case of Kleine-Levin Syndrome

J Korean Neurol Assoc > Volume 17(5); 1999 > Article

Journal of the Korean Neurological Association 1999;17(5): 705-709.

Kleine-Levin 증후군 1예

이승훈, 이성훈*김상윤

서울대학교 의과대학 신경과학교실,연정 뇌기능 수면 연구소*

A Case of Kleine-Levin Syndrome

Seung-Hoon Lee, M.D., Sung-Hoon Lee, M.D.*, Sang-Yun Kim, M.D.

Department of Neurology, Seoul National University, College of Medicine , Yonjung Brain Function & Sleep Research Center*

Abstract

Kleine-Levin syndrome (KLS) is a rare disorder and is diagnosed by recurrent episodes of hypersomnia, hyperpha-gia, and neurobehavioral dysfunctions. We present a case of a male 19 year-old with seven episodes of the above symp-toms. All episodes occurred after a respiratory infectious illness and spontaneously resolved after a few days or a few weeks. A polysomnography showed prolonged sleep latency and decreased REM sleep (14.6%). A multiple sleep laten-cy test revealed a slightly short mean sleep latency (8min 7sec) and three sleep-onset REM episodes in a series of four sleep latency tests across a one day period. The electrophysiological features of previously reported were reviewed. J Kor Neurol Ass 17(5):705~709, 1999