Regional Cerebral Blood Flow in Patients with Delayed Carbon ?Monoxide encephalopathy

J Korean Neurol Assoc > Volume 13(3); 1995 > Article

Journal of the Korean Neurological Association 1995;13(3): 605-610.

지연성 일산화탄소 뇌병증 환자의 국소 뇌혈류량

이상수, 한문구, 정중택, 한설희, 궁성수

충북대학교 신경과, 핵의학과

Regional Cerebral Blood Flow in Patients with Delayed Carbon ?Monoxide encephalopathy

Sang Soo Lee, M.D., Moon Ku Han, M.D., Joong Taek Chung, M.D., Seol Heui Han, M.D., Sung Soo Koong, M.D.

Department of Neurology, Nuclear Medicine, College of Medicine, Chungbuk National University

Abstract

Delayed hypoxic encephalopathy is one of the most important neurologic sequelae in carbon monoxide (CO) poisoning. Regional cerebral blood flow (CBF) of cerebral cortices were measured in five patients with delayed CO encephalo'pathy confirmed by clinical features and magnetic resonance imaging (MRI) and five normal persons using ""'Tc-HMPAO SPECT (technetium 99m hexamethylpropylene amine oxide single photon emission computed tomography). For the quantitative analysis, six pairs of region of interest in cerebral cortices and cerebellar hemispheres were determined. Among five regions to cerebellar ratios, those of superior and inferior frontal, parietal, and temporal cortices were significantly reduced (p