A Patient with Thyrotoxic Autoimmune Encephalopathy

J Korean Neurol Assoc > Volume 19(6); 2001 > Article

Journal of the Korean Neurological Association 2001;19(6): 665-668.

Thyrotoxic Autoimmune Encephalopathy 1예

서상원, 이병인 이종두*박선아 김규식 김서현

연세대학교 의과대학 신경과,핵의학과*

A Patient with Thyrotoxic Autoimmune Encephalopathy

Sang Won Seo, M.D., Byung In Lee, M.D., Jong Doo Lee, M.D.*, Sun Ah Park, M.D., Kyu Sik Kim, M.D., Seo Hyun Kim, M.D.

Department of Neurology, and Nuclear Medicine* College of Medicine, Yonsei University

Abstract

Hashimoto’s encephalopathy is a steroid responsive relapsing disorder associated with high titers of thyroid-related autoantibodies that presents with subacute progressive dementia and myoclonus. Although most patients reported have been either euthyroid or hypothyroid at the time of presentation, we present a patient with Hashimoto’s encephalopathy with thyrotoxicosis that was successfully managed with steroids and antihyperthyroid therapy. We recommend that encephalopathy presented in patients with hyperthyroidism should be tested with thyroid-related autoantibodies and managed with steroid and antihyperthyroid therapy. Key Words : Hashimoto’s encephalopathy, Thyrotoxicosis, Thyroid-related autoantibodies