One case of Subacute Sensory Neuropathy Associated with
Primary Sjogren’s Syndrome

J Korean Neurol Assoc > Volume 17(5); 1999 > Article

Journal of the Korean Neurological Association 1999;17(5): 735-740.

원발성 Sjogren 증후군에 동반된 아급성 감각 신경병 1예

정원희, 정근호 ·한동균 ·박희정 ·조필자 ·김승민*·선우일남*

국립의료원 신경과,연세대학교 의과대학 신경과학교실*

One case of Subacute Sensory Neuropathy Associated with Primary Sjogren’s Syndrome

Won Hee Chung, M.D., Keun Ho Chung, M.D., Dong Gyun Han, M.D., Heue Jung Park, M.D., Phil Za Cho, M.D., Seung Min Kim, M.D.*, Il Nam Sunwoo, M.D. *

Department of Neurology, National Medical Center, Seoul, Korea Department of Neurology, Yonsei University College of Medicine, Seoul, Korea*

Abstract

Subacute sensory neuropathies associated with primary Sjogren’s syndrome have been reported rarely. We describe a woman with primary Sjogren’s syndrome who developed a widespread, pure sensory neuropathy with a subacute onset. An electrophysiological study showed the typical absence or decreased amplitude of sensory nerve action poten-tials (SNAPs). A sural nerve biopsy showed a loss of large myelinated fibers and axonal degeneration without inflam-mation. The clinical course of long-standing subacute sensory neuropathy, the biopsy-documented axonal degeneration, and the neurophysiological findings suggest involvement of the dorsal root ganglia. J Kor Neurol Ass 17(5):735~740, 1999 Key Words : Peripheral neuropathy, Sjogren’s syndrome, Sensory neuropathy, Dorsal root ganglia