A Case of Limbic Encephalitis Associated with Small Cell Lung ?Cancer-About Diagnostic MRI Findings-

J Korean Neurol Assoc > Volume 12(2); 1994 > Article

Journal of the Korean Neurological Association 1994;12(2): 338-342.

폐소세포암과 동반된 Limbic Encephalitis 경험 1예 (MRI 소견을 ?중심으로)

조태영, 곽용태,김윤중,이병인,허균

연세대학교 신경과.

A Case of Limbic Encephalitis Associated with Small Cell Lung ?Cancer-About Diagnostic MRI Findings-

Tae Young Cho, M.D., Yoon Jung Kim, M.D., Byung In Lee, M.D., Kyun Huh, M.D.

Department of Neurology, Yonsei University College of Medicine

Abstract

Limbic encephalitis is a rare paraneoplastic syndrome characterized by prominent memory impairment, affective and behavioral disturbances, and progressive intellectual deterioration. Among many different neoplasm known to cause limbic encephalitis, a small cell lung cancer is certainly the most frequently reported. We experienced a 64-years old male patient presented with clinical features consistent with limbic encephalitis. He was subsequently found to have small cell lung cancer and showed characteristic evolutional MRI features ; increased signal intensity on T2 weighted image in the bilateral medial temporal regions during early stage and progressive severe atrophy in the late stage.