Encephalitis Lethargica With Catatonia

J Korean Neurol Assoc > Volume 28(3); 2010 > Article

Journal of the Korean Neurological Association 2010;28(3): 209-213.

긴장증을 동반한 기면뇌염

장영희, 한일우 a 나해리 b 김상윤

서울대학교 의과대학 신경과학교실, 분당서울대학교병원 신경과, 효자병원 신경과 a , 보바스기념병원 신경과 b

Encephalitis Lethargica With Catatonia

Young Hee Chang

Department of Neurology, Seoul National University College of Medicine, Clinical Neuroscience Center, Seoul National University Bundang Hospital, Seoul, Korea Department of Neurology a , Hyoja Geriatric Hospital, Yongin, Korea Department of Neurology b , Bobath Memorial Hospital, Seongnam, Korea

Abstract

Encephalitis lethargica (EL) is an acute or subacute central nervous system (CNS) infectious disorder presenting with pharyngitis followed by sleep disorder, basal ganglia signs (particularly parkinsonism), and neuropsychiatric sequelae. We report a 67-year-old man who had hypersomnolence, oculogyric crisis, akinetic mutism, parkinsonism, and malignant catatonia, which represented the stereotypic movement disorder with additional features of hyperthermia. His symptoms dramatically improved after steroid pulse therapy, indicating that EL syndrome could be a postinfectious neurological autoimmune CNS disorder. Key Words: Encephalitis, Catatonia, Parkinsonism