J Korean Neurol Assoc > Volume 17(4); 1999 > Article
Journal of the Korean Neurological Association 1999;17(4): 588-590.
산발성 기면성 뇌염 2예
이규환, 정태익 ·김혜식 ·김지훈 ·한시령 ·김영인 ·이광수
가톨릭대학교 의과대학 신경과학교실
Two Cases of Sporadic Encephalitis Lethargica
Kyu-Hwan Lee, M.D., Tae-Ik Chung, M.D., Hye-Sik Kim, M.D., Chi-Hun Kim, M.D., Si-Ryung Han, M.D., Young-In Kim, M.D., Kwang-Soo Lee, M.D.
Department of Neurology, the Catholic University of Korea
Abstract
We present two patients with clinical features suggestive of a hyperkinetic form of encephalitis lethargica described by von Economo. While undergoing treatment for viral meningoencephalitis, they both developed comatose mentality, oromandibular dyskinesia, chorea, myoclonic jerk, oculogyric crisis, opistotonus, respiratory failure, and autonomic dysfunction. One patient died of autonomic failure while the other improved several months later. In both patients, cerebrospinal fluid exmamination revealed only pleocytosis. A brain MRI and EEG showed no specific findings. In order to control severe hyperkinetism and autonomic failure, medical treatments including L-dopa, clonazepam, and steroid pulse therapy were administereed in both cases while electroconvulsive therapy was tried in one of the cases. However, they all failed. These cases and previous reports informed us of the presence of sporadic form of encephalis J Kor Neurol Ass 17(4):588~590, 1999 Key Words : Sporadic Encephalitis Lethargica, Viral Encephalitis, Extrapyramidal Symptom


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