| 한국 뇌졸중 자료은행에 등록된 10,811명의 급성기 허혈성 뇌졸중 환자 분석: 병원기반 다의료기관 전향적 자료등록 연구 |
| 유경호, 배희준t 권순억b 강동화b 홍근식c 이용석d 나정호e 구자성a 김종성b 김진혁
이주헌 조수진 황성희 정 산 한문구f 조기현g 김병채g 신동진h 장대일I 박재현c 김응규c
정대수j 안무영k 이대희l 박건우l 김용재m 이경열n 허지회n 김승현o 이광호p 정진상p 차재관q 이준홍r 엄근용s 이병철 노재규f |
| 한림대학교 의과대학 신경과학교실 |
| Analysis of 10,811 Cases with Acute Ischemic Stroke from Korean Stroke Registry: Hospital-Based Multicenter Prospective Registration Study |
| Kyung-Ho Yu |
| Department of Neurology, Hallym University College of Medicine; Department of Neurology, Eulji University School of Medicinea; Department of Neurology, University of Ulsan College of Medicineb; Department of Neurology, Inje University College of Medicinec; Department of Neurology, Seoul National University Boramae Hospitald; Department of Neurology, Inha University College of Medicinee; Department of Neurology, Seoul National University College of Medicinef; Department of Neurology, Chonnam National University Medical Schoolg; Department of Neurology, Gachon Medical Schoolh; Department of Neurology, Kyunghee University College of Medicinei; Department of Neurology, Pusan National University College of Medicinej; Department of Neurology, Soonchunhyang University College of Medicin다; Department of Neurology, Korea University College of Medicinel; Department of Neurology, Ewha Womans University College of Medicinem; Department of Neurology, Yonsei University College of Medicinen; Department of Neurology, Hanyang University College of Medicineo; Department of Neurology, Sungkyunkwan University School of Medicinep; Department of Neurology, Dong-A University College of Medicineq; Department of Neurology, National Health Insurance Corporation Ilsan Hospitalr; Department of Neurology, KwangMyungSungAe Hospitals; Department of Neurology, Bundang Seoul National University Hospitalt |
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| Abstract |
Background: Although several hospital-based stroke studies were published, there has not been any reliable data representing the clinical characteristics of stroke in Korea. We analyzed the clinical characteristics of patients with ischemic stroke registered in the Korean Stroke Registry (KSR), which is the largest prospective hospital-based nation-wide stroke registry in Korea.
Methods: The KSR provided standardized protocols for collecting data, which includes the data of demographics, subtypes of stroke, risk factors, and neurological outcome at discharge. The brain imaging studies, including CT or MRI, were performed in all cases.
Results: KSR registered 10,811 patients of acute ischemic stroke between Nov. 2002 and Jun. 2004. The large-artery atherosclerosis was the most common subtype (37.3%), followed by small vessel occlusion (30.8%). Hypertension (65.4%) was the most common risk factor, followed by smoking (34.5%) and diabetes (28.3%). Although most of the hypertensive and diabetic patients had been diagnosed before the stroke, less than 45.4% and 32.5% of them were under regular control. The steno-occlusive lesion of extracranial carotid artery was only 29.3% and the ratio of intra- to extracranial artery disease was more than 2 in KSR. Only 20.5% of patients were admitted within 3 hours after stroke onset and 2.1% were treated with intravenous thrombolysis. In-hospital case-fatality was 5.2%, which is relatively comparable to those of previous studies.
Conclusions: The KSR provided informative data in understanding the clinical characteristics of ischemic stroke in Korea. Further analysis of KSR will facilitate clinical trials and development of guidelines for the management of stroke patients.KeyWords:Cerebrovascular disorder, Epidemiology, Registries |
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