| 알츠하이머병과 혈관성치매환자의 행동심리적 증상의 차이 |
| 김태유, 김수영a 김응규b 김재우c 박경원b 성상민d 손태홍e 안경숙a 유봉구f 윤수진g 윤성민h
이상찬i 정해관j 최문성k 홍태용 부산?경남치매학회 |
| 김해한솔요양병원, 경성대학교 사회복지학과a, 인제대학교 부산백병원b, 동아대학교 의료원c, 부산의료원d, 신라대학교 가족학과e,
고신대학교 복음병원f, 성균관대학교 마산삼성병원g, 마산태봉병원h, 동의의료원i, 성균관대학교 의과대학 사회의학교실j, 메리놀병원k |
| The Differences of Behavioral and Psychological Symptoms in the Patients of Alzheimer's Disease and Vascular Dementia |
| Tae-You Kim |
| Department of Neurology, Gimhae Hansol Hospital, Gimhae; Department of Social Welfare, Kyung Sung Universitya, Busan; Department of Neurology, Inje University College of Medicineb, Busan; Department of Neurology, Dong-A University College of Medicinec, Busan; Department of Neurology, Busan Medical Centerd, Busan; Department of Family Stuides, Silla Universitye, Busan; Department of Neurology, Kosin University College of Medicinef, Busan; Department of Neurology, Sungkyunkwan University of Medicine Masan Samsung Hospitalg, Masan; Department of Neurology, Masan Taebong Hospitalh, Masan; Department of Neurology, Dong-eui Medical Centeri, Busan; Department of Social and Preventive Medicine, School of Medicine, Sungkyunkwan Universityj, Suwon; Department of Neurology, Maryknoll Hospitalk, Busan, Korea |
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| Abstract |
Background: Behavioral and psychological symptoms (BPSD) are common in dementia. These may be helpful for clinical differentiation between Alzheimer's disease (AD) and vascular dementia (VD). Most previous studies have reported the prevalence and severity of BPSD regardless of severity of progression. However, we evaluated the differences of BPSD by grading dementia progression and including severe cases only.
Methods: 141 dementia outpatients from clinics of Busan-Gyeongnam Dementia Association in Korea were analyzed. All patients were administered the Korean version of the Neuropsychiatric Inventory (K-NPI), the expanded version of Korean Clinical Dementia Rating Scale (CDR), and the Korean version of Mini-Mental State Examination (K-MMSE).
Results: There were 95 patients with AD and 46 patients with VD. AD patients revealed higher frequency of manifested BPSD symptoms and most of subscales showed higher composite scores also. But apathy was more severely and frequently manifested in VD. AD patients had more frequent night-time behavior and aberrant motor symptoms above 3 point in CDR 0.5 and VD patients had more frequent apathy symptom above 3 point in CDR 1.
Conclusions: These results suggest that generally AD patients revealed more frequent and severe BPSDs than VD patients. Apathy was a more dominant symptom in VD. It seemed that some of the symptoms were valuable clues for the differential diagnosis even though a better designed study was required.KeyWords:Alzheimer's disease, Vascular dementia, Behavioral symptom |
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