J Korean Neurol Assoc > Volume 19(2); 2001 > Article

Journal of the Korean Neurological Association 2001;19(2): 167-169.

긴장 연축을 단독 증상으로 나타낸 다발성 경화증 1예

이보람, 나해리 정 산 유경호 마효일 이병철

한림대학교 의과대학 신경과학교실

"A Case of Tonic Spasm Presenting as Sole Manifestation of Multiple Sclerosis"

"Bo-Ram Lee, M.D., Harry Na, M.D., San Jeong, M.D., Kyung-Ho Yu, M.D., Hyeo-Il Ma, M.D., Byung-Chul Lee, M.D."

Department of Neurology, Hallym University College of Medicine

Abstract

"A young woman developed a hemilateral tonic spasm associated with multiple sclerosis. Her symptoms included brief recurrent episodes of abnormal, often painful, posturing of one or more extremities without alteration of consciousness. An area of demyelination in the contralateral cerebral peduncle was observed on a magnetic resonance imaging. The tonic attacks abated with carbamazepine therapy. The pathophysiology may involve ephaptic transmission between demyelinated fibers in acute plaques within the corticospinal tract secondary to axonal irritation by lymphokines. J Korean Neurol Assoc 19(2):167~169, 2001 Key Words : Multiple sclerosis, Spasm, Ephaptic transmission"