J Korean Neurol Assoc > Volume 19(2); 2001 > Article

Journal of the Korean Neurological Association 2001;19(2): 143-148.

알쯔하이머병과 혈관성치매의 신경심리학적 감별

김돈수, 함동석*·곽용태*·한일우*

건양대학교 신경과학교실,용인효자병원 신경과

"Neuropsychological Differentiation between Alzheimer’s Disease and Vascular Dementia"

Don Soo Kim, M.D., Dong Seok Hahm, M.D.*, Yong Tae Kwak, M.D.*, Il Woo Han, M.D.*

Department of Neurology, Konyang University Hospital, Yongin Hyoja Geriatric Hospital*

Abstract

"Background : Neuropsychological Differentiation between Alzheimer’s disease and vascular dementia has been con-troversial. The aim of this study was to detect neuropsychological differences between Alzheimer’s disease (AD) and vascular dementia (VD). Methods : Twenty one patients who met the criteria for probable AD according to the National Institute of Neurological Disorders and Stroke and the Alzheimer’s Disease and Related Disorders Association (NINCDS-ADRDA) and 22 patients who met criteria for probable VD according to the National Institute of Neurological Disorders and Stroke and the Association Internationale pour la Recherche et l’Enseignement en Neurosciences (NINDS-AIREN), were included in this study. These two dementia groups were matched for age, sex, education, Mini-Mental State Examination score, and severities of dementia. All patients underwent the Seoul Neuropsychological Screening Battery (SNSB). R e s u l t s : Patients with VD showed greater deficits in verbal fluency (P<.05) than AD patients. However, AD patients, compared with VD patients, showed greater deficits in verbal memory functions including the 3 words recall task. Otherwise, no significant between-group differences were found in task results. C o n c l u s I o n s : Neuropsychologically, patients with VD differ from patients with AD only in a few cognitive domains. J Korean Neurol Assoc 19(2):143~148, 2001 Key Words : Alzheimer disease, Vascular dementia, Neuropsychological test"