A Case of Myasthenia Gravis associated with Idiopathic Thrombocytopenic Purpura

J Korean Neurol Assoc > Volume 18(4); 2000 > Article

Journal of the Korean Neurological Association 2000;18(4): 508-511.

특발성 혈소판 감소성 자반병과 동반된 중증 근무력증 1예

한동균, ·선우일남*·박희정 ·이상현 ·조필자 ·정근호†

국립의료원 신경과,연세대학교 의과대학 신경과학교실*,이진의원 신경과†

A Case of Myasthenia Gravis associated with Idiopathic Thrombocytopenic Purpura

Dong Gyun Han, M.D., Il Nam Sunwoo, M.D.*, Heue Jung Park, M.D., Sang Hyeon Lee, M.D., Phil Za Cho, M.D., Keun Ho Chung, M.D.†

Department of Neurology, National Medical Center Department of neurology, Yonsei University College of Medicine* Department of Neurology, Lee & Jin’s Medical Clinic†

Abstract

Myasthenia gravis has been associated with a variety of autoimmune diseases, but the association of myasthenia gravis with idiopathic thrombocytopenic purpura has been rarely reported. A previously healthy 33-year-old female presented with a 10-month history of easy fatigability, motor weakness, diplopia and menorrhage. Clinical and labora-tory findings supported the diagnosis of myasthenia gravis and idiopathic thrombocytopenic purpura. After a thymecto-my, there were surprising improvements not only in muscle strength, but also of thrombocytopenia. Though this associ ?ation may be incidental, the patient’s progress suggests that idiopathic thrombocytopenic purpura may be closely relat-ed to myasthenia gravis immunologically because both diseases developed simultaneously and showed good therapeu-tic responses after a thymectomy. J Korean Neurol Assoc 18(4):508~511, 2000 Key Words : Myasthenia gravis, Idiopathic thrombocytopenic purpura, Autoimmune diseases