A Case of Methanol Intoxication with Multifocal Enhancing Lesions in Brain Magnetic Resonance Imaging

J Korean Neurol Assoc > Volume 18(3); 2000 > Article

Journal of the Korean Neurological Association 2000;18(3): 330-332.

메탄올 중독 1예

윤창본 김명권 강성수 박현미 정환모 신동진, 윤창본 김명권 강성수 박현미 정환모 신동진

가천의과대학 중앙길병원 신경과학교실

A Case of Methanol Intoxication with Multifocal Enhancing Lesions in Brain Magnetic Resonance Imaging

Chang-Bon Yun, M.D., Myung-Kwon Kim, M.D., Sung-Soo Kang, M.D., Hyeon-Mi Park, M.D., Hwan-Mo Jeong, M.D., Dong-Jin Shin, M.D.

Department of Neurology, Gil Medical Center, Gachon Medical School

Abstract

In accidental or suicidal methanol ingestion, bilateral necrosis of the putamen and hemispheric white matter lesions are the most common findings on CT and MRI. There are a few reports that have demonstrated abnormal CT findings in methanol intoxication, however, to our knowledge, contrast enhancement of these lesions have not been reported in Korea. We report the case of a 36-year-old male who had a brain MRI performed 3 weeks after accidental methanol intoxication. T2 weighted MRI showed bilateral symmetrical high signal lesions in the frontal lobe and basal ganglia with hemorrhaegic necrosis. A postcontrast MRI demonstrated multifocal enhancing lesions in both frontal lobes, right temporal lobe, both basal ganglias and both cerebellar hemispheres. We suggest that the characteristic brain MRI find-ing and careful history taking are helpful in diagnosis of methanol intoxication. J Korean Neurol Assoc 18(3):330~332, 2000 Key Words : Methanol intoxication, MRI, Multifocal enhancing lesions