Two Cases of Marchiafava-Bignami Disease

J Korean Neurol Assoc > Volume 17(5); 1999 > Article

Journal of the Korean Neurological Association 1999;17(5): 764-766.

Marchiafava-Bignami disease 2예

오병철, 양윤정 ·김영현*

전북대학교 의과대학 신경과학교실,의과학 연구소*

Two Cases of Marchiafava-Bignami Disease

Byeong Cheol Oh, M.D., Yun Jeong Yang, M.D., Young Hyun Kim, M.D.*

Department of Neurology, Chonbuk National University Medical School and Institute for Medical Sciences*

Abstract

We described 2 patients with Marchiafava-Bignami disease, a neurological disorder associated with chronic alcohol consumption. Patient 1 expressed general weakness and confusion, while patient 2 expressed dysphagia and seizures. Lesions involving the corpus callosum were identified with T2 weighted MR imaging in which there was a hyperinten-sity in the splenium of patient 1 and in the entire corpus callosum of patient 2. While the conditions of both patients were improved by with nutritional support, they were left with cognitive impairment. J Kor Neurol Ass 17(5):764~766, 1999 Key Words : Marchiafava-Bignami disease, Corpus callosum, Demyelination