6 cases of postinfectious opsoclonus in adult

J Korean Neurol Assoc > Volume 15(6); 1997 > Article

Journal of the Korean Neurological Association 1997;15(6): 1285-1292.

성인에서 보인 감염후성 안간대 6례 보고

이은아, 주인수, 오명수, 김장성, 허균

아주대학교 의대 신경과

6 cases of postinfectious opsoclonus in adult

Eun Ah Lee, M.D. , In Soo Joo, M.D. , Myeong Soo Oh, M.D. , Jang Sung Kim, M.D. , Kyoon Huh, M.D.

Dept of Neurology, School of Medicine, Ajou University

Abstract

Opsoclonus is the involuntary, repetitive, rapid conjugate ocular movements occurring in all directions that are irregular in amplitude and frequency. The cause of opsoclonus are idiopathic, paraneoplastic or postinfectious. Opsoclonus of the postinfectious origin often accompanies other abnormal movements such as tremor, myoclonus and ataxia, and shows a relatively benign course with good response to steroid. Six patients who suffered from myalgia, chilling, fever, cough and generalized weakness fior one to two weeks prior to the admission, experienced visual disturbance, gait unsteadiness and clumsiness of the upper extremities,, Prominent opsoclonus, tremulous movements of trunk and limbs, and intermittent myoclonus were observed. These symptoms markedly improved several days following the use of ACTH or dexametasone.