| Opsoclonus 3례 |
| 김진호, 이영진,권순희,이명식,최일생 |
| 연세대학교 신경과. |
| Three Cases of Opsoclonus |
| Jin Ho Kim, M.D., Young Jin Lee, M.D., Soon Hee Kwon, M.D., Myung Sik Lee, M.D., Il Saing Choi, M.D |
| Department of Neurology, Yongdong Severance Hospital, Yonsei University College of Medicine, |
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| Abstract |
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Opsoclonus introduced in 1913, by Orzechowski is a disorder of eye movements ch ractenzed by involuntary bursts of multidirectional saccades without an intersaccadic I terval and persistulg during sleep, is often accompained by myoclonic jerks of the face and body. It is a rare condition, the common causes of which are viral encephalitides and a paraneoplastic manifestation of an occult malignant neoplasm The sites of the responsible lesion, however, hez been a matter of controversy: cerebellum midbrain, thalamus, thalamus and midbrain, has been suggested, as well as a combination of several sites in the central nervous system We present three cases of opsoclonus with brief review of literatures. The first and second case, suspected vural infection, presented with prodromal symptoms(fever, headache, sore throat), ataxia and opsoclonus. Clinical manifestations improved with clonazepam therapy, Tbe thlrd case is 9 month old male presented with vomiting, inguinal hernia, opsoclonus and poor nutrition. The brain CT scan revealed tumor at pons and midbrain. |
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