A clinical study on the seizures following spontaneously occurred lobar intracerebral hemorrhage

J Korean Neurol Assoc > Volume 15(5); 1997 > Article

Journal of the Korean Neurological Association 1997;15(5): 974-979.

자연 발생 엽상뇌출혈 후 발생하는 경련에 대한 임상적 연구

이성현, 이상수, 한설희

충북대학교 의대 신경과

A clinical study on the seizures following spontaneously occurred lobar intracerebral hemorrhage

Sung-Hyun Lee, M.D, Sang-Soo Lee. M.D., Seol-Heui Han , M.D.

Dept of Neurology, College of Medicine, Chungbuk National University.

Abstract

To investigate the factors affecting the development of seizures after spontaneously occurred lobar intracerebral hemorrhage (ICH) such as size, location, and onset age of hemorrhage and clinical feature of those seizures, we analyzed 34 patient with spontaneously occurred lobar ICH in the respect of seizures retrospectively. From October 1991 to March 1994, 41 patient were admitted to the Chungbuk National University Hospital with spontaneously occurred lobar ICH. Among them, 2 patients died within 7days after ICH and 5 patients could not be followed adequately by any means. Finally we analyzed 34 patients whom we followed up at least 3 yrs except 2 patients (one had seizures at 7 month and 8 month after ICH then lost follow up; the other with no seizure died 25 months after ICH). Seizures occurred in 8 out of 34 (23.5%) patients, 2patients within 2 weeks, 4within 1 year, and 2 within 3years. Three patients showed generalized tonic clonic seizure and 5 partial seizure with secondary generalization. All patients with seizures were satisfactorily managed by single antiepileptic drug. Their EEG findings are as follows, 1 patient normal; 1 generalized slowing; 4 localized slowing; 2 localized spikes. Size (p = 0.74), location (p = 0.52), and age of onset (p = 0.74) of lobar ICH are not different between patients with seizures and ones without seizures. This study suggests that medically controllable seizures develop in relatively high portion of patients with spontaneous lobar ICH could not predict the occurrence of epileptic seizures in this group of patients.