J Korean Neurol Assoc > Volume 15(1); 1997 > Article
Journal of the Korean Neurological Association 1997;15(1): 30-35.
자발성 뇌출혈 환자에서 뇌출혈의 양을 결정하는 인자에 관한 연구
정선주, 김종성, 양대웅, 윤성숙
울산대학교 의과대학 아산재단 서울중앙병원 신경과
Factors determining the volume of the spontaneous intracerebral hemorrhage
Sun Ju Chung, M.D., Jong Sung Kim, M.D., Dae Woong Yang, M.D., Sung Sug Yoon, R.N.
Department of Neurology, University of Ulsan, Asan Medical Center, Seoul, Korea
Abstract
Background and purpose : Hypertension and alcohol consumption are well known independent risk factors of spontaneous intracerebral hemorrhage (ICH). However, it is uncertain whether controlling of them reduces the volume of ICH. Furthermore, it remains also unkown whether other factors such as age, sex, education level, smoking, diabetes mellitus, and previous history of stroke are related to the volume of ICH. This study was designed to evaluate the relations of those things with the volume of ICH. Methods : We prospectively assessed above items in 103 consecutive patients with ICH aged 33 to 87 years (mean age : 64 years, 50 men and 53 women ). We divided the volume of ICH with the use of CT scan into small (<10cc, n=71) and large (>=l0cc, n=32) groups. Results : The patients with previous history of stroke significantly have a smaller volume of ICH compared to those without (p=0.04). However, the other factors (age, sex, education level, antihypertensive medication, alcohol consumption, smoking, and diabetes mellitus) were not significantly correlated with the volume of ICH to multivariate analysis. The patients with previous history of stroke tended to receive more regular antihypertensive medication than these without (p-0.06). Conclusion : The patients with previous history of stroke have a smaller volume of ICH possibly due to adequate antihypertensive treatment. However, the other factors which we evaluated were not significantly correlated with the volume of ICH.


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