A Case of Hypertrophic Pachymeningitis Caused by Tuberculosis

J Korean Neurol Assoc > Volume 14(4); 1996 > Article

Journal of the Korean Neurological Association 1996;14(4): 1051-1054.

결핵에 의한 비후성 두개 경막염 1례

박기철, 한범기 이지용 김승민 허철 정순희

연세대학교 원주의과대학 신경과학교실, 신경외과학교실, 병리학교실

A Case of Hypertrophic Pachymeningitis Caused by Tuberculosis

Ki Chul Park, M.D., Bum Ki Han, M.D., Ji Young Lee, M.D., Seung Min Kim, M.D., Chul Hu, M.D., Soon Hee Jung, M.D.

Department of Neurology, Neurosurgery and Pathology, Wonju College of Medicine, Yonsei University

Abstract

Hypertrophic pachymeningitis is a rare disorder, with idiopathic, tuberculosis, syphilis and sarcoidosis being the most commonly considered etiology. We experienced a case of hypertrophic pachymeningitis caused by tuberculosis a 34-year old female. She had complained of consistent headache and diplopia for 20 days. The characteristic finding on magnetic resonance imaging was marked thickening of the unilateral cerebellar tentorium with gadolinium-DTPA enhancement. There was no significant changes on adjacent brain parenchyma. Histologic investigation of the left cerebellar tentorium disclosed chronic granulomatous inflammation with central caseous necrosis. The patient was successfully managed with anti-tuberculosis drugs.