Cramp Fasciculation Syndrome

J Korean Neurol Assoc > Volume 14(4); 1996 > Article

Journal of the Korean Neurological Association 1996;14(4): 1030-1034.

근육경련 섬유속성연축 증후군

김용덕, 이명식

연세대학교 의과대학 영동세브란스병원 신경과

Cramp Fasciculation Syndrome

Yong Duk Kim, M. D., Myung Sik Lee, M. D.

Department of Neurology, Yongdong Severance Hospital, Yonsei University College of Medicine

Abstract

Cramp-fasciculation syndrome can be characterized by acute onset of action induced muscle cramps without weakness or muscle atrophy. The neurological examination is normal except for fasciculation or myokymia. Electromyography (BMG) shows fasciculation and muscle biopsy may show neurogenic abnormalities. We describe a 65 years old woman who had muscle cramps and fasciculations in the hands and bilateral feet for 2 months. Laboratory studies including CBC, erythrocyte sedimentation rate, serum electrolytes, blood chemistries, creatinekinase, serum magnesium, serum ionized calcium, thyroid function tests, parathyrold function tests, urinalysis were all normal. Motor and sensory nerve conduction studies were normal. EMG study showed fasciculation in the right abductor pollicis brevis muscle and the bilateral anterior tibialis muscles There were no showers of electrical potentials following the M-wave after repetitive median, ulnar, and peroneal nerve stimulations at the frequency of 1, 2, and 5-Hz. She improved dramatically after vitamin E treatment.