| 전이성 뇌종양의 임상양상 및 영상진단 소견 |
| 권오영, 임병훈, 이영배* 이규용* 김희태* 김승현* 김주한* 김명호* |
| 경상대학교 의과대학 신경과학교실 , 한양대학교 의과대학 신경과학교실* |
| Clinical and Radiological Evaluation of Metastatic Brain Tumor |
| O. Y. Kwon, M.D., B. H. Lim, M.D.,Y. B. Lee, M.D.*, K. Y. Lee, M.D.*, H. T. Kim, M.D.*, S. H. Kim, M.D.*, J. H. Kim, M.D.*, M. H. Kim, M.D.* |
| Department of Neurology, Gyeongsang University College of Medicine
Department of Neurology, Hanyang University College of Medicine |
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| Abstract |
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The definition of metastatic brain tumor designates all intracranial neoformations that are originated from a peripheral cancer and propagated by a metastatic process (Paillas and Pellet, 1975) . According to this definition, metastatic brain tumors comprised nodules that were developed in the brain, the Aura mater and the cranial nerves; they did not include metastases to the skull even when tumors compressed the brain, or cases of carcinomatous meningoradiculitis in which there was no ultimate formation of true tumors. We evaluated 132 out of 412 patients with metastatic brain tumor and analyzed clinical and radiological manifestations by reviewing chart and CT or MRI. The
number of patients with malignant cancer was 21s13 from January 1989 to June 1994 at Hanyang university hospital. Brain metastases was found in 412 patients among them. One hundred thirty-two out of 412 patients were available for this study. The primary sites were lungs (50%) , gastrointestinal tract(10.6%), breast(9.1%), etc., in order of frequency. Symptoms included headache (43.9%), motor weakness(14.4%), loss of consciousness(4.6%), and nausea and vomiting(4.6%), etc.. One hundred cases(75.8%) of metastatic tumor were located in supratentorial area, 16 cases in infratentorial and 16
cases in both. Intraparenchymal metastases were 118 cases(81.4%) and extraparenchymal were 10 (7.6%) . Four cases (3.0%) were located in intra-and extraparenchymal regions. Among intraparenchymal metastases, corticomedullary .junction (90.7%) was the most common sloe. Multiple metastarses were 82(62.1%) and metastases with single focus were 50(37.9 %) . Parietal lobe(36.0 %) was the most common site for single metastasis. Regarding tumor nature, 75 (56.8%) was solid, 24(18.2%) hemorrhagic, 20(15.2%) necrotic, 8(6.1%) cystic, 4(3.0%) necrotic and hemorrhagic, 1 (0.8%) calcific. Contrast enhancement was seen on CT or MRI In 107 cases(81.1%) . In 30 cases (22.7%) , diagnosis of metastasis preceded that of primary tumor. Our data may be useful to understand epidemiologic pattern of metastatic brain tumors and helpful to diagnose them. |
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