A Case of Bezafibrate-induced Myopathy

J Korean Neurol Assoc > Volume 13(4); 1995 > Article

Journal of the Korean Neurological Association 1995;13(4): 996-1000.

Bezafibrate에 의한 급성 근병증을 보인 1예

박은미, 박기덕, 황신이, 문준식, 최경규, 구혜수

이화여자대학교 신경과. 해부병리학교실

A Case of Bezafibrate-induced Myopathy

Eun Mi Park, M.D., Kee Duk Park, M.D., Shin Yi Hwang, M.D., Joon Shik Moon, M.D., Kyung Gyu Choi, M.D., Hae Soo Koo, M.D.

Department of Neurology, and Pathology, College of Medicine, Ewha Womans University

Abstract

One case of bezafibrate-induced myopathy was experienced and presente with a brief review of literatures. A 80-year-old woman with diabetes mellitus developed generalized myalgia and chest tightness 2 days before admission. The patient was -treated with bezafibrate (800mg/day) for the previous 3 months. Serum creatine kinase, LDH and AST were markedly increased. Muscle biopsy revealed type 2 fiber atrophy. Withdrawal of the drug under the impression of bezafibrate-induced myopathy was followed by rapid clinical improvement