Internuclear Ophthalmoplegia (Clinicoradiological Study of 12 ?Cases)

J Korean Neurol Assoc > Volume 12(3); 1994 > Article

Journal of the Korean Neurological Association 1994;12(3): 506-511.

핵간안동마비 12례에 대한 임상 및 방사선학적 연구

남현우, 전범석,노재규,명호진,박성호,이한보

서울대학교 신경과. 보라매병원 신경과.

Internuclear Ophthalmoplegia (Clinicoradiological Study of 12 ?Cases)

H.W. Nam, M.D., B.S. Jeon, M.D., J.K. Roh, M.D., H.J. Myung, M.D.

Department of Neurology, College of Medicine, Seoul National University

Abstract

We reviewed 12 patients with internuclear ophthalmoplegia (INO), of which 2 were bilateral. The etiologies were cerebrovascular disease, hemorrhage of cavernous hemangioma, and bacterial meningitis. Their main presentig symptom was diplopia and many of them showed long tract and brainstem dysfunction signs other than INO. Brain MRI revealed peraqueductal lesions in the pontine tegmentum and most of the patients improved over 3 month period. In Korea, cerebrovascular disease is the main cause of INO even in young patients and in those with bilateral INO.