Clinical Analysis of Spinal Leukemia

J Korean Neurol Assoc > Volume 10(2); 1992 > Article

Journal of the Korean Neurological Association 1992;10(2): 143-149.

척추백혈병의 임상적고찰

김영인, 이광수,강민수,정성우,김범생,이종욱,한치화,박종원,김춘추,김동집

가톨릭대학교 신경과, 내과.

Clinical Analysis of Spinal Leukemia

Yeoung-In Kim, M.D., Kwang-Soo Lee, M.D., Min-Soo Kang, M.D., Sung-Woo Chung, M.D., Beum-Saeng Kim, M.D., Jong-Wook Lee, M.D., Chi-Wha Han, M.D., Jong-Won Park, M.D., Choon-Choo Kim, M.D., Dong-Jip Kim, M.D.

Department of Neurology and Internal Medicine, College of Medicine, Catholoic University

Abstract

As advances in the treatment of leukemia lead to further prolongation of the life span, secondary involvement of the nervous system becomes increasingly important. Especially spinal cord or cauda equina compression by leukemic cell is a medical emergency because delay in treatment often results in irreversible paralysi,s and loss of sphinctercontrol. The hospital records of 10 patients, who were admitted to the St. Mary's hospital of CUMC from January 1, 1988 to September 30, 1989 with the diagnosis of spinal leukemia were analyzed retrospectively and the results were obtained as follows; 1. The sex ratio(M: F) of the patients was 9 :1 and the age distribution rarlged from eighteen to fifty-six years with a mean age of 34.5 years. 2. The most common symptoms were pain, urinary difficulty, sensory change, and weakness etc. 3. The segment of spine involved was, approximately. 31% thoraic. 54% lumbar, and 15 % sacral. 4. Response to radiation treatment was excellent in 8 patients(80% ) especially in early treated group within 3days.