Paroxysmal Nocturnal Hemoglobinuria Presenting as Cerbral Venous Sinus Thrombosis and Acute Renal Failure -A Case Report-

J Korean Neurol Assoc > Volume 9(1); 1991 > Article

Journal of the Korean Neurological Association 1991;9(1): 116-119.

뇌정맥동 혈전증 및 급성신부전증으로 발현된 발작성 야간혈색소뇨증 1예

홍승희, 배재천,조필자

국립의료원 신경과.

Paroxysmal Nocturnal Hemoglobinuria Presenting as Cerbral Venous Sinus Thrombosis and Acute Renal Failure -A Case Report-

Seung Hee Hong, M.D., Jae Chun Bae, M.D., Phil Za Cho, M.D.

Dep. Of Neurology, National Medical Center

Abstract

Cerebral venous sinus thrombosis and acute renal failure are well known cornplications of paroxysmal nocturnal hemoglobinuria(PNH). 53 year old rnan was admitted to the hospital because of headache and gerleralized convulsion. Contrast enharlced CT scan revealed empty delta sign in superior sagital sinus and acute renal failure developed within 2 weeks of admissiorL The diagnosis of PNH depended on positive HAM test and low leukocyte alkaline phosphatase(LAP). The prognosis was relativley good on the treatrnent with anticoagulant, anticonvulsant, antiplatelets and steroid.