Two Cases of Rhinocerebral Mucormycosis with Perineural Extension to the Pons

J Korean Neurol Assoc > Volume 17(6); 1999 > Article

Journal of the Korean Neurological Association 1999;17(6): 895-900.

신경조직을 따라 뇌교로 전파된 비뇌 털곰팡이증 2예

심용수, 나정호 ·권지현 ·하충건

인하대학교 의과대학 신경과학교실

Two Cases of Rhinocerebral Mucormycosis with Perineural Extension to the Pons

Yong-Soo Shim, Joung-Ho Rha, Jee-Hyun Kwon, Choong-Kun Ha

Department of Neurology, College of Medicine, Inha University

Abstract

Rhinocerebral mucormycosis is a very rare, but mostly fatal fungal infection, usually found in diabetic or other immunocompromised hosts. It has a characteristic pattern of spread, invasion of vessel walls with subsequent local thrombotic infarction or direct invasion. But we found two cases contrast to these typical patterns of spread. Our cases initially originated in the nasal cavity and progressed to the cavernous sinus in usual manner, but after then, extended along the trigeminal nerve into the pons. MRI demonstrated the perineural spread, which was confirmed by pathology. J Korean Neurol Assoc 17(6):895~900, 1999 Key Words : Rhinocerebral mucormycosis, Perineural extension, Pons, Trigeminal nerve