A Case of Essential Thrombocytosis with Cerebral Infarction

J Korean Neurol Assoc > Volume 11(4); 1993 > Article

Journal of the Korean Neurological Association 1993;11(4): 614-618.

본태성 혈소판 혈증과 동반된 뇌경색 1례

유남태, 이진석,하정숙,하충건,임병훈

경상대학교 신경과.

A Case of Essential Thrombocytosis with Cerebral Infarction

Nam-Tae Yoo, M.D., Jin-Suk Lee, M.D., Jung-Sook Ha, M.D., Choong-Kun Ha, M.D., Byung-Hoon Lim, M.D.

Department of Neurology, College of Medicine Gyengsang National University

Abstract

Essential thrombocytosis (ET) is a clonal myeloproliferative disorder, characterized predominantly by a markedly elevated platelet count without known cause. We report a case of essential thrombocytosis, the only clinical manifestation of which consisted of neurologic symptoms, including headache, dysarthria, right hemiparesis with a relatively benign and slowly progressive clinical course. Neuroradiologic examination (Brain CT and MRI) disclosed a multiple infarction in the both basal ganglia and left parietal region. These findings are discussed in relation to the possible pathogenetic mechanisms of the vascular occlusion due to abnormal platelet function in ET