Acute Monocular Ophthalmoplegia Associated with Anti-GQ1b IgG Antibody

J Korean Neurol Assoc > Volume 22(6); 2004 > Article

Journal of the Korean Neurological Association 2004;22(6): 663-665.

항 GQ1b 항체와 연관된 급성 단안성 외안근마비

구대림, 박기형 김희태 이규용 이영주

한양대학교 의과대학 신경과학교실

Acute Monocular Ophthalmoplegia Associated with Anti-GQ1b IgG Antibody

Dae-Lim Koo

Department of Neurology, Hanyang University Collage of Medicine, Guri, Korea

Abstract

Some authors found the anti-GQ1b IgG antibody in some of their patients with acute postinfectious ophthalmoparesis without ataxia, “atypical MFS” or “acute ophthalmoparesis (AO)”. Antecedent illness, acute ophthalmoparesis, CSF albuminocytologic dissociation, and the anti-GQ1b IgG antibody are useful markers for diagnosing AO. AO can be considered a variant or atypical form of MFS. We report two monocular AO patients who had the anti-GQ1b IgG antibody along with a literature review. Key Words: Acute ophthalmoplegia, Anti-GQ1b IgG antibody, Miller Fisher syndrome