Effect of Plasmapheresis on Guillain-Barre Syndrome

J Korean Neurol Assoc > Volume 11(4); 1993 > Article

Journal of the Korean Neurological Association 1993;11(4): 521-526.

Guillain-Barre 증후군에서 혈장교환술의 효과

조용원, 임정근,이동국,이상도,박영춘

계명대학교 신경과.

Effect of Plasmapheresis on Guillain-Barre Syndrome

Yong-Won Cho, M.D., Jeong-Geun Lim, M.D., Dong-Kuck Lee, M.D., Sang-Doe Yi, M.D., Young-Choon Park, M.D.

Department of Neurology, College of Medicine Keimyung University

Abstract

The present study was designed to evaluate a beneficial effect of plasmapheresis on Guillain-Barre syndrome comparing wth the combined therapy(plasmapheresis and steroid and/or gamma globulin). Exchange fluid used for plasmapheresis was fresh frozen plasma and the amount of exchanged plasma was 40-50ml/kg in each exchange for 3 to 5 times. Plasmapheresis had been of benefit on Guillain-Barre syndrome. Without serious adverse effect. But there was no difference between the effect of plasmapheresis and the combined therapy.