Intravascular Lymphomatosis in Central Nervous System

J Korean Neurol Assoc > Volume 19(4); 2001 > Article

Journal of the Korean Neurological Association 2001;19(4): 413-416.

중추신경계에 발생한 혈관 내 림프종증

한병인, 배명철 홍지만 허이균 한재호*

아주대학교 의과대학 신경과학교실,해부병리학교실*

Intravascular Lymphomatosis in Central Nervous System

Byung-In Han, M.D., Myung Cheol Bae, M.D., Ji-Man Hong, M.D., Kyoon Huh, M.D. Jae Ho Han, M.D.*

Departments of Neurology, Pathology* Ajou University School of Medicine

Abstract

"Intravascular lymphomatosis (IL) is a variant of non-Hodgkin’s lymphoma with an predilection for the CNS. Most cases are not diagnosed until postmortem. IL is characterized by neoplastic proliferation of lymphoid cells within the lumen of small veins and arteries with minimal involvement of the parenchyma. We experienced a 62-year-old woman who presented with seizure and fever associated with anemia, elevated LDH and beta 2-microglobulin without systemic involvement. This report illustrates the diagnostic challenge of this rare disorder with a grave prognosis. J Korean Neurol Assoc 19(4):413~416, 2001 Key Words : Intravascular lymphomatosis, beta 2-Microglobulin, Lactate dehydrogenase"