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Journal of the Korean Neurological Association 2006;24(6): 585-588.
Morvan 증후군 1예
김선경, 권석범 권기한 정 산 황성희
한림대학교 의과대학 신경과학교실
A Case of Morvan Syndrome
Seon-Gyeong Kim
Department of Neurology, Hallym University College of Medicine, Seoul, Korea
Abstract
Neuromyotonia, or Isaacs’ syndrome, consists of continuous muscle fiber activity caused by hyperexcitability of the peripheral nerves. Rarely, these patients also develop CNS symptoms characterized by confusion, insomnia, hallucinations, and agitation. A rare disease consisting of neuromyotonia, autonomic symptoms, and CNS dysfunction is called Morvan’s syndrome. We report a 24-year-old man who presented with insomnia, malaise, anorexia, hyperhidrosis, palpitation and myokymia in both the lower extremities. The pathomechanism of Morvan’s syndrome is related to the voltage-gated K+ channel (VGKC) antibodies.KeyWords:Lsaacs’ syndrome, Neuromyotonia, Morvan’s syndrome