J Korean Neurol Assoc > Volume 18(4); 2000 > Article
Journal of the Korean Neurological Association 2000;18(4): 483-485.
신경절교종과 연관된 Lennox-Gastaut 증후군 환자의 수술적 치료 1예
류지연, ·강중구 ·이정교*·이상암
울산대학교 의과대학 서울중앙병원 신경과,신경외과*
Lennox-Gastaut Syndrome Associated with Gangliocytoma : A Case of Surgical Treatment
Ji Yeon Ryu, M.D., Joong-Koo Kang, M.D., Jung-Kyo Lee, M.D.*, Sang-Ahm Lee, M.D.
Department of Neurology and Neurosurgery*, Asan Medical Center, College of Medicine, University of Ulsan
Abstract
We report a case of Lennox-Gastaut syndrome successfully treated by the removal of hippocampal gangliocytoma. A17-year-old girl was admitted due to intractable tonic seizure, generalized tonic clonic seizure, and frequent fallingdespite the administration of polypharmacotherapy. She was mentally retarded and had developmental delays. She had the first seizure at the age of 12 months and the pattern of seizures seemed to be drop attacks. Electroencephalogram (EEG) showed background slowing of about 7 Hz, multifocal spike and wave, and generalized spike and wave complex-es (1.5~3.5 Hz). Magnetic resonance image (MRI) revealed a small polycystic mass in the left parahippocampal gyrus and hippocampal atrophy. A left hippocampectomy and total resection of the tumor was performed. Histopathologically, the cysts were identical to gangliocytoma. Sixth months later, the frequency of seizures decreased to once a month No seizures have been reported since August 1998. J Korean Neurol Assoc 18(4):483~485, 2000 Key Words : Lennox-Gastaut syndrome, Gangliocytoma, Seizure, Surgical treatment


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