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Case Report
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J Korean Neurol Assoc. 2026;44(2):159-162. Published online May 1, 2026.
DOI: https://doi.org/10.17340/jkna.2026.0011
- Leptomeningeal Myelomatosis Manifesting as Isolated Aphasia
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Sejin Park1, Jong-Geun Seo1,2
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1Department of Neurology, Kyungpook National University Hospital, Daegu, Korea
2Department of Neurology, School of Medicine, Kyungpook National University, Daegu, Korea
- 전실어증으로만 발현된 연수막골수종증
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박세진1, 서종근1,2
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- Corresponding author: Jong-Geun Seo ,Tel: +82-53-420-5765, Fax: +82-53-422-4265, Email: jonggeun.seo@gmail.com
- Received: February 7, 2026; Revised: March 12, 2026 Accepted: March 18, 2026.
- Abstract
- Leptomeningeal myelomatosis represents an uncommon but clinically consequential form of extramedullary disease. Because its manifestations frequently overlap with vascular and infectious conditions, timely recognition is challenging. In particular, isolated speech disturbance without accompanying motor deficits can be misattributed to acute ischemic stroke or focal seizures, potentially delaying appropriate therapy. Here, we report a case of 81-year-old female patients presenting with global aphasia. In this case, brain magnetic resonance imaging and cerebrospinal fluid study including cytology demonstrated leptomeningeal involvement by multiple myeloma.
Keywords :Leptomeningeal, Multiple myeloma, Aphasia
- 초록
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