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J Korean Neurol Assoc. 2012;30(1):10-14.
- Comparison of Electroencephalography and Diffusion-Weighted MR
Findings in Transient Global Amnesia Patients
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Kwang Ki Kim
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Department of Neurology, Dongguk University Ilsan Hospital, Goyang, Korea
- 일과성완전기억상실증 환자에서 뇌파와
확산강조MR영상 비교
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김광기, 정상욱 노상미 정일영
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동국대학교 일산병원 신경과
- Abstract
- Background
The etiology of transient global amnesia (TGA) is uncertain. Recent studies have demonstrated a high signal
intensity on diffusion MRI in TGA patients. In this study we reviewed and compared the use of electroencephalography
(EEG) and diffusion-weighted imaging (DWI) in TGA in order to determine their sensitivity and to reveal clues about the
etiology of this condition.
Methods
Twenty patients (7 males and 13 females; aged 58.0±12.1?years, mean±SD) who had been diagnosed with TGA
at Dongguk University International Hospital within a 2-year period (2007 and 2008) were included in the study. All
patients underwent EEG and DWI.
Results
The EEG of 12 of the 20 patients (60.0%) exhibited abnormalities; all 12 exhibited slowing on either the left side
(n=6) or bilaterally (n=6). Spikes or sharp waves were detected in two patients. DWI revealed unilateral high signal
intensities in the hippocampus of eight patients; five of these patients had left hippocampal lesions, and the other three
had right hippocampal lesions. Four patients with a unilateral DWI lesion exhibited bilateral EEG abnormalities, and six
patients exhibited only EEG abnormalities (without DWI abnormalities). Three patients had a high-signal-intensity
lesion on DWI without EEG abnormalities. Five patients had normal EEG and DWI results. Interestingly, no patient had
EEG abnormalities confined to the right temporal area.
Conclusions
These findings suggest that left temporal dysfunction is important for the development of TGA. EEG might
be complementary to DWI in TGA investigations, and may be superior at illustrating the associated memory dysfunction. Key Words: Transient global amnesia, Electroencephalography, Diffusion-weighted MRI
Keywords :
- 초록
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