안구증상으로 발현한 Lambert-Eaton Myasthenic Syndrome (LEMS)

J Korean Neurol Assoc > Volume 28(1); 2010 > Article

Journal of the Korean Neurological Association 2010;28(1): 50-52.

Lambert-Eaton Myasthenic Syndrome (LEMS) Presented With Ocular Symptoms

한우호, 석정임 이규철 권오대 김숙영a

대구가톨릭대학교 의과대학 신경과학교실, 안과학교실a

안구증상으로 발현한 Lambert-Eaton Myasthenic Syndrome (LEMS)

Woo Ho Han

Department of Neurology and Ophthalmologya, Catholic University of Daegu, School of Medicine, Daegu, Korea

Abstract

Lambert-Eaton myasthenic syndrome (LEMS) is characterized clinically by fluctuating muscular weakness; presentation with ocular symptoms is unusual. A 60-year-old man had developed diplopia and ptosis 2?years previously. The findings of a neurologic examination were normal except for bilateral ptosis and ophthalmoplegia. The amplitude of compound muscle action potentials recorded on the abductor digiti minimi increased (by more than 500%) during 50-Hz stimulation. This case demonstrates that LEMS should be included in the differential diagnosis of myasthenic symptom confined to the ocular muscles. KeyWords: Lambert-Eaton Myasthenic Syndrome, Diplopia, Ptosis