보툴리눔독소의 근육내주사 이후 발생한 의인성 보툴리눔독소증

J Korean Neurol Assoc > Volume 28(1); 2010 > Article

Journal of the Korean Neurological Association 2010;28(1): 47-49.

Iatrogenic Botulism After Intramuscular Injection of Botulinum Toxin Type A

유준상, 선우일남 신하영 고혜선 예병석 김승민

연세대학교 의과대학 신경과학교실

보툴리눔독소의 근육내주사 이후 발생한 의인성 보툴리눔독소증

Joon-Sang Yoo

Department of Neurology, Yonsei University College of Medicine, Seoul, Korea

Abstract

Botulinum toxin type A (BTA) is widely used for both medical treatment and cosmetic purposes. A 46-year-old woman presented with progressive generalized weakness and dysphagia. The patient had injected BTA into her both of her calves by herself for cosmetic purposes. Repetitive nerve stimulation of the right facial nerve demonstrated reduced compound muscle action potential amplitudes of the orbicularis oculi and nasalis muscles, and a reduced response to low-frequency, repetitive stimulation. The possibility of iatrogenic botulism should be considered when using BTA. KeyWords:Iatrogenic botulism, Repetitive nerve stimulation test