Central Pontine Myelinolysis Presenting With Cerebellar Ataxia

J Korean Neurol Assoc > Volume 27(3); 2009 > Article

Journal of the Korean Neurological Association 2009;27(3): 264-267.

소뇌증상으로 발현한 중심교뇌수초용해증

김의중, 오선영 최하철 임미혜 신병수

전북대학교 의학전문대학원 신경과학교실

Central Pontine Myelinolysis Presenting With Cerebellar Ataxia

Eui-Joong Kim

Department of Neurology, Collage of Medicine, Chonbuk National University, Jeonju, Korea

Abstract

Central pontine myelinolysis (CPM) is a neurologic disorder that is usually related to rapid correction of hyponatremia and chronic alcoholism. CPM involves concentrated, symmetric, noninflammatory demyelination within the central pons; this pathology also occurs in extrapontine regions. Frequently observed clinical manifestations are sudden weakness, dysphagia, dysarthria, loss of consciousness, and locked-in syndrome. We describe herein a case of CPM predominated by cerebellar signs without typical symptoms, but with involvement of the cerebellum or cerebellar peduncle. Key Words: Central pontine myelinolysis (CPM), Cerebellar ataxia