Dementia With Lewy Bodies Diagnosed by Cognitive Fluctuation After Anticholinergic Medication

J Korean Neurol Assoc > Volume 26(3); 2008 > Article

Journal of the Korean Neurological Association 2008;26(3): 254-258.

항콜린제 투여 후 발현된 인지기능 기복이진단에 도움이 된 루이소체 치매

구본대, 유한욱

관동대학교 의과대학 명지병원 신경과학교실

Dementia With Lewy Bodies Diagnosed by Cognitive Fluctuation After Anticholinergic Medication

Bon D. Ku

Department of Neurology, Myongji Hospital, Kwandong University College of Medicine, Goyang, Korea

Abstract

Dementia with Lewy bodies (DLB) usually presents with progressive cognitive decline and parkinsonism. We report a 68-year-old man who showed parkinsonism including resting tremor and mild cognitive decline. After anticholinergic medication, he showed recurrent visual hallucination. Neuropsychological tests revealed frontal and memory impairments. PET showed hypometabolism in the primary visual and visual association cortices. It is necessary to consider the possibility of DLB as well as anticholinergic side effect when visual hallucination occurs during the treatment of parkinsonism.KeyWords:Dementia with Lewy bodies, Visual hallucination, Anticholinergics