A Pathology-proven Case of Schilder's Disease

J Korean Neurol Assoc > Volume 26(1); 2008 > Article

Journal of the Korean Neurological Association 2008;26(1): 50-54.

병리조직 검사로 확인된 쉴더병

김병수, 김병준 이광호 김경문

성균관대학교 의과대학 삼성서울병원 신경과학교실

A Pathology-proven Case of Schilder's Disease

Byung-Su Kim

Department of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea

Abstract

Schilder’s disease or myelinoclastic diffuse sclerosis (MDS) is a rare variant of multiple sclerosis. We report a 66-year-old woman with progressive motor weakness and diffuse white matter degeneration on MRI, which satisfies the Poser’s restrictive criteria of MDS. As previously reported cases of probable Schilder’s disease did not meet the criteria correctly, we consider our patient is the first pathology-proven case of MDS in Korea.KeyWords:Diffuse sclerosis, Demyelinating disease, White matter

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