Relapsing Herpes Simplex Encephalitis

J Korean Neurol Assoc > Volume 25(3); 2007 > Article

Journal of the Korean Neurological Association 2007;25(3): 393-397.

재발성 단순포진바이러스 뇌염 1예

장우영, 오기욱 김현영 한광수 김희태 김승현 김주한

한양대학교 의과대학 신경과학교실

Relapsing Herpes Simplex Encephalitis

Wooyoung Jang

Department of Neurology, college of Medicine, Hanyang University, Seoul, Korea

Abstract

Herpes simplex encephalitis (HSE) is the most common type of viral encephalitis and a fourteen day administration of acyclovir is well-known as the treatment of choice for HSE. Occasionally HSE relapses, but rarely with acyclovir treatment. We report a case of relapsing HSE after treatment with acyclovir for 14 days. Our case suggests that patients with progressive high signal intensities in diffusion-weighted brain MRIs might need longer antiviral therapy over 14 days for preventing the relapse of herpes simplex encephalitis. KeyWords:Herpes simplex encephalitis, Relapse, Diffusion weighted image