A Case of Isolated Traumatic Caudate Lesion with Marked Improvement in Visuospatial Function by Donepezil

J Korean Neurol Assoc > Volume 25(3); 2007 > Article

Journal of the Korean Neurological Association 2007;25(3): 377-380.

도네페질로 시공간 능력의 호전 경과를 보인 외상성 꼬리핵 병소 1예

강명찬, 이상훈 안태범 박기정 윤성상 장대일 정경천

경희대학교 의과대학 신경과학교실

A Case of Isolated Traumatic Caudate Lesion with Marked Improvement in Visuospatial Function by Donepezil

Myung-Chan Kang

Department of Neurology, Kyung Hee University College of Medicine, Seoul, Korea

Abstract

Visuospatial dysfunction after isolated caudate lesion and improvement by donepezil has not been reported. Herein we report a 46-year old woman with visuospatial dysfunction after an isolated traumatic caudate lesion. Memory impairment and visuospatial dysfunction with normal frontal executive functioning was found in the first neuropsychological test. Her brain MRI showed an isolated right caudate lesion in the dorsal portion. Donepezil was prescribed. On follow-up neuropsychological testing, memory and visuospatial function increased by more than 100% from the base line. KeyWords:Caudate nucleus, Trauma, Donepezil