Imaging Evidence of Basal Ganglia Pathology in Hemi choreoballistic Movement of the Patient with Nonketotic Hyperglycemia: Case Report with Serial Follow Up of Neuroimages

J Korean Neurol Assoc > Volume 23(1); 2005 > Article

Journal of the Korean Neurological Association 2005;23(1): 117-120.

비케톤성 고혈당증에 의한 편무도성 운동 환자의 기저핵 이상: 신경영상 추적 검사 1예

박찬희, 이동현 윤미진* 박수철 이종두* 최일생

연세대학교 의과대학 신경과학교실, 핵의학교실

Imaging Evidence of Basal Ganglia Pathology in Hemi choreoballistic Movement of the Patient with Nonketotic Hyperglycemia: Case Report with Serial Follow Up of Neuroimages

Chan Hee Park

Department of Neurology and Nuclear Medicine*, Yonsei University College of Medicine, Seoul, Korea

Abstract

The mechanism of chorea underlying nonketotic hyperglycemia was controversial. Serial follow up of brain MRI, 99mTc-ECD SPECT, and 18F-FDG PET in conjunction with clinical observation was done to clarify the pathologic localization. From the functional neuroimages, according to the clinical improvement, the relevant pathology was localized on the lentiform nucleus, mainly on the putamen. In caudate, the mismatch between glucose metabolism and blood flow was observed during and after choreoballistic movement which suggested an important cue to understand the pathogenesis of chorea.KeyWords:Hyperglycemia, Chorea, Putamen