A Case of Lower Motor Neuron Syndrome Which May be Paraneoplastic

J Korean Neurol Assoc > Volume 22(3); 2004 > Article

Journal of the Korean Neurological Association 2004;22(3): 265-268.

방종양성으로 추정되는 하부운동신경원 증후군 1예

전상범, 임영민 김광국

울산대학교 의과대학 신경과학교실

A Case of Lower Motor Neuron Syndrome Which May be Paraneoplastic

Sang Beom Jeon

Department of Neurology, University of Ulsan College of Medicine, Seoul, Korea

Abstract

We present a 55-year-old man who has a six-month history of progressive weakness of all limbs. Findings from neurologic examination were notable for a diffuse muscular weakness and atrophy in all limbs. Laboratory findings for collagen vascular disease, monoclonal gammopathy, and infections were normal. Electrophysiologic studies supported lower motor neuron (LMN) syndrome. CT scan and needle biopsy disclosed small cell lung cancer. This case suggests that in some elderly patients with LMN syndrome a careful search for an underlying cancer is warranted. Key Words:Paraneoplastic syndromes, Lower motor neuron disease, Lung cancer