A Case of Critical Illness Myopathy

J Korean Neurol Assoc > Volume 21(6); 2003 > Article

Journal of the Korean Neurological Association 2003;21(6): 679-682.

Critical illness myopathy 1예

김영대 , 선우일남 최혜연 한상돈 신하영 김승민 김태승

연세대학교 의과대학 신경과학교실, 병리학교실

A Case of Critical Illness Myopathy

Young-Dae Kim

Department of Neurology and pathology*, Yonsei University College of Medicine

Abstract

Critical illness myopathy (CIM) is characterized by generalized flaccid weakness occurring in patients with severe systemic illness. A 27-year-old woman presented with loss of consciousness and dyspnea. The brain MRI suggested Wernicke's encephalopathy. During treatment, she experienced progressive quadriparesis and respiratory muscle weakness, which required the mechanical ventilation. The muscle pathology of vastus lateralis revealed type 2 muscle fiber atrophy on histochemical stain and selective loss of myosin on electron microscopic study, and suggested clinical diagnosis of critical illness myopathy. Key Words: Critical illness, Myopathy