A Case of Parkinsonism Caused by Acetone Intoxication

J Korean Neurol Assoc > Volume 21(4); 2003 > Article

Journal of the Korean Neurological Association 2003;21(4): 422-424.

아세톤에 의해 발생한 파킨슨증후군 1예

성임숙 , 권오영*† 강희영* 김동환* 김영수* 박기종*† 최낙천*† 임병훈*†

경상대학교 의과대학 신경과학교실*, 경상대학교 건강과학연구원†

A Case of Parkinsonism Caused by Acetone Intoxication

Imsuk Sung

"Department of Neurology, Gyeongsang National University College of Medicine* Gyeongsang Institute of Health Science, Gyeongsang National University†"

Abstract

"A variety of toxins cause parkinsonism and the lesions are primarily in the pallidostriatum. It usually does not respond to levodopa. We experienced a patient whose parkinsonian features developed after accidental acetone ingestion. She had rigidity, bradykinesia, gait disturbance and her speech was sluggish. Brain MRI showed bilateral basal ganglionic lesions. She was treated with levodopa and her neurological symptoms improved. To our knowledge, there has not been any previous reports of acetone causing parkinsonism. Acetone may cause parkinsonism by damaging the basal ganglia. Key Words: Parkinsonian disorders, Acetone, Basal ganglia"