Rofecoxib에 반응을 보인 발작성 반두통 2예

J Korean Neurol Assoc > Volume 21(3); 2003 > Article

Journal of the Korean Neurological Association 2003;21(3): 304-306.

Two Cases of Paroxysmal Hemicrania with Response to Rofecoxib

도진국 , 김지언 이동국

대구가톨릭대학교 의과대학 신경과학교실

Rofecoxib에 반응을 보인 발작성 반두통 2예

Jin Kuk Do

Department of Neurology, School of Medicine, Catholic University of Daegu

Abstract

"Paroxysmal hemicrania (PH) has been recently defined as an uncommon primary headache. PH is characterized by frequent attacks of severe unilateral pain associated with autonomic symptoms. The attack frequency usually ranges from 5 to 40 attacks per day. PH is characterized by its absolute responsiveness to indomethacin. However, indomethacin is not often well tolerated because of its gastric side effects. We report two patients with PH who could not tolerate indomethacin due to its severe gastric side effects but dramatically responded to rofecoxib.Key Words: Paroxysmal hemicrania, Indomethacin, Rofecoxib"