A Case of Hyperthyroid Myopathy Due to Graves Disease

J Korean Neurol Assoc > Volume 21(1); 2003 > Article

Journal of the Korean Neurological Association 2003;21(1): 111-114.

Graves 병에 의한 갑상선기능항진증성 근병증 1예

조광덕 , 김진엽 김수진 박양순 안성기

울산대학교 의과대학 강릉아산병원 신경과, 진단병리과

A Case of Hyperthyroid Myopathy Due to Graves Disease

Kwang Deog Jo

"Department of Neurology, Internal Medicine* and Diagnostic Pathology, Kangnung Asan Hospital, Department of Neurology and Family Medicine, Seoul Asan Hospital, Asan Medical Center, University of Ulsan College of Medicine"

Abstract

"A 49-year-old woman was admitted with a three-month history of myalgia and progressive proximal and distal mus-cle weaknesses. Physical examination showed diffuse enlargement of the thyroid gland and mild muscle atrophy. Serum creatine kinase was slightly increased and electromyography showed a myopathic pattern. Muscle biopsy showed non-specific myopathic changes. Serum thyroid-stimulating hormone was very low, whereas thyroxine (T4) was greatly increased as well as anti-thyroglobulin, anti-microsome, and TSH-receptor antibody. The patient ?s symptoms were improved during the treatment with propilthiouracil.Key Words : Myopathy, Hyperthyroidism, Graves　 disease"